Platelet count is a key indicator in routine clinical blood tests and is prone to spurious abnormalities affected by multiple factors. Among them

spurious normality of platelets is easily overlooked as the value falls within the reference range

which carries potential risks in diagnosis and treatment. This paper reports a laboratory case of spurious normality of platelet count in a healthy individual undergoing physical examination. The examinee had no underlying medical history or clinical symptoms. Initial screening of platelets by the impedance method in routine blood analysis yielded a result of 159×10

9

/L

which was within the normal range. However

the instrument flagged an abnormal platelet histogram

accompanied by abnormal indicators such as microcytic hypochromic anemia and anisocytosis. Based on morphological features of the histogram

laboratory personnel promptly performed a recheck using the highly specific low platelet count optical channel

supplemented by blood smear microscopy for verification. Finally

the initial platelet result was confirmed to be spuriously normal

with the true count being 62×10

9

/L. The core of this case lies in the precise identification of interference during the diagnostic process

enabling clinicians to administer targeted treatment accordingly. Through analysis of this case

it is emphasized that laboratory staff should attach importance to instrument alarm information and histogram interpretation

be familiar with testing principles

standardize review procedures

and rationally apply optical channels and microscopic review. These measures can effectively prevent the reporting of spurious platelet results

improve laboratory accuracy

and ensure the safety of clinical diagnosis and treatment.