Thyroid storm triggered by upper respiratory tract infection in a patient with extremely low body mass index: A case analysis

CHEN Dongmiao; WANG Congrong

doi:10.65948/DICM20260515.0004

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Thyroid storm triggered by upper respiratory tract infection in a patient with extremely low body mass index: A case analysis

更新时间：2026-08-07

- Thyroid storm triggered by upper respiratory tract infection in a patient with extremely low body mass index: A case analysis
- Intelligent Digital Clinical Medicine Pages: 1-5(2026)
- 作者机构：
  
  南方医科大学南方医院增城院区检验医学科，广州 511340
- 作者简介：
  
  Email: Wang Congrong（congrongwang@smu.edu.cn）
- 基金信息：
- DOI：10.65948/DICM20260515.0004
  CLC：
- Received：15 May 2026，
  
  Revised：2026-05-28，
  
  Online First：31 July 2026，
- 稿件说明：
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陈东妙,王从容.极低体质量甲状腺功能亢进症患者上呼吸道感染诱发甲状腺功能亢进危象的病例分析[J].数智医学,

CHEN Dongmiao,WANG Congrong.Thyroid storm triggered by upper respiratory tract infection in a patient with extremely low body mass index: A case analysis[J].Intelligent Digital Clinical Medicine,
陈东妙,王从容.极低体质量甲状腺功能亢进症患者上呼吸道感染诱发甲状腺功能亢进危象的病例分析[J].数智医学, DOI：10.65948/DICM20260515.0004.

CHEN Dongmiao,WANG Congrong.Thyroid storm triggered by upper respiratory tract infection in a patient with extremely low body mass index: A case analysis[J].Intelligent Digital Clinical Medicine, DOI：10.65948/DICM20260515.0004.

摘要

患者，女，23 岁，甲状腺功能亢进症（简称甲亢）病程1年且未接受规范治疗，因轻微上呼吸道感染诱发病情急剧进展，48 h内进展为甲状腺功能亢进危象（thyroid storm，TS）。患者入院查体BMI仅15.8 kg/m²，就诊期间相继出现窦性心动过速、心肌损伤、肝功能受损、低钾血症等多系统受累典型临床表现。通过临床快速诊断并紧急予以其系统性综合救治，患者病情得到快速有效控制。本病例提示，长期未经管控的甲亢患者机体耐受能力下降，轻微呼吸道感染可诱发TS，极低BMI可作为此类危象发生的重要风险标志，为临床早期识别和处理此类急症提供关键见解，有助于优化管理策略以改善患者预后。

Abstract

A 23-year-old female patient with a 1-year history of untreated hyperthyroidism presented with rapid deterioration triggered by mild upper respiratory tract infection

and progressed to thyroid storm (TS) within 48 hours. Physical examination upon admission revealed that her BMI was merely 15.8 kg/m². During hospitalization

she developed typical manifestations of multisystem involvement including sinus tachycardia

myocardial injury

liver dysfunction and hypokalemia successively. Rapid clinical diagnosis and urgent systematic comprehensive treatment were implemented

resulting in prompt and effective control of her condition. This case suggests that patients with long-term uncontrolled hyperthyroidism have reduced bodily tolerance

and mild respiratory tract infection may trigger TS. Extremely low BMI can serve as an important risk marker for the occurrence of such crisis. This report provides critical insights for early clinical identification and management of this emergency

and facilitates the optimization of management strategies to improve patient prognosis.

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references

Ursem S R , den Elzen W P J , van den Berg J M , et al . Natural course of subclinical hyperthyroidism in primary care in the Netherlands [J ] . Eur Thyroid J , 2025 , 14 ( 6 ): e250142 .

Inman B L , Long B . Thyrotoxicosis [J ] . Endocrinol Metab Clin North Am , 2026 , 55 ( 1 ): 83 - 98 .

Kopp P A , Giordani I , Feldt-Rasmussen U , et al . Approach to the patient with thyroid storm [J ] . J Clin Endocrinol Metab , 2026 , 111 ( 5 ): 1484 - 1494 .

Hamed M , Palumbo S , Mendha T . Severe cardiovascular effects of prolonged untreated hyperthyroidism manifesting as thyroid storm [J ] . Cureus , 2022 , 14 ( 6 ): e26289 .

Khongsaengbhak T , Atthakitmongkol T , Tanwandee T . Liver dysfunction in hyperthyroidism [J ] . Hepat Med , 2024 , 16 : 81 - 89 .

Tamang A , Sapkota P , Humagain S , et al . Hyperthyroid hypokalemic periodic paralysis in a Nepali male: A case report [J ] . Clin Case Rep , 2025 , 13 ( 10 ): e71023 .

de Mul N , Damstra J , Nieveen van Dijkum E J M , et al . Risk of perioperative thyroid storm in hyperthyroid patients: A systematic review [J ] . Br J Anaesth , 2021 , 127 ( 6 ): 879 - 889 .

Hodgson J A , Pittman B P , Solomon J B , et al . Postoperative thyroid storm after evacuation of a complete hydatidiform mole: A case report [J ] . A A Pract , 2021 , 15 ( 7 ): e01495 .

Liu J , Zhang W . Double plasma molecular adsorption system combined with plasma exchange successfully treated thyroid storm and severe liver injury: A case report [J ] . Medicine (Baltimore) , 2025 , 104 ( 51 ): e46686 .

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