同济大学附属东方医院南院检验科,上海 200123
论文通信作者:赵晓明(ppumm@126.com)
收稿:2026-04-22,
修回:2026-05-22,
录用:2026-07-07,
网络首发:2026-07-10,
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葛羽,赵晓明.一例贫血患者疑难AB亚型血型鉴定及临床分析[J].数智医学,
GE Yu,ZHAO Xiaoming.Identification and Clinical Analysis of a Rare AB Subtype Blood Group in an Anemic Patient[J].Intelligent Digital Clinical Medicine,
葛羽,赵晓明.一例贫血患者疑难AB亚型血型鉴定及临床分析[J].数智医学, DOI:10.65948/DICM20260422.0001.
GE Yu,ZHAO Xiaoming.Identification and Clinical Analysis of a Rare AB Subtype Blood Group in an Anemic Patient[J].Intelligent Digital Clinical Medicine, DOI:10.65948/DICM20260422.0001.
患者,女,53岁,半年前活动后出现气喘,伴胸闷,2周前气喘症状加重,并呈现贫血貌。结合既往史、心电图、妇科超声、血常规和铁测定,诊断为缺铁性贫血, 窦性心动过速,高血压 2级(很高危),高脂血症,子宫肌瘤。血型鉴定过程中,患者红细胞与抗B抗体反应减弱,并无输血史或移植史,无白血病等血液病史,亦无特殊用药史,考虑血型亚型。经进一步鉴定,确认为AB亚型。鉴于ABO亚型患者异体输血需极为慎重,非必要不输血,且其贫血原因为缺铁性贫血,予以补充铁剂治疗,患者状态平稳,无明显不适。
The patient presented with a six-month history of exertional dyspnea and chest tightness
which had exacerbated over the past two weeks
accompanied by an anemic appearance. Based on the clinical history
electrocardiogram
gynecological ultrasound
and laboratory findings (including complete blood count and iron studies)
the patient was diagnosed with iron-deficiency anemia
sinus tachycardia
grade 2 hypertension (very high risk)
hyperlipidemia
and uterine fibroids. During the blood grouping process
the patient’s red blood cells exhibited weakened reactivity with anti-B antibodies. Given the absence of prior blood transfusions
transplants
hematologic malignancies (such as leukemia)
or specific medication history
an ABO subgroup was suspected and subsequently confirmed as an AB subgroup through further identification. Considering that allogeneic transfusion should be approached with extreme caution in patients with ABO subgroups and that the anemia was primarily iron-deficient in nature
iron supplementation was administered. The patient remained clinically stable with no significant adverse symptoms following treatment.
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胡艳 . 40例ABO血型抗原减弱的血清学表现及原因分析 [J ] . 中国医药指南 , 2020 , 18 ( 20 ): 101 - 102 .
李敏芳 , 刘峰 . 采用全自动血型仪正反定型不一致的原因分析及对策 [J ] . 临床输血与检验 , 2013 , 15 ( 1 ): 54 - 56 .
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